Edouard (Eddy) A. PHILIPPE, Ph.D.  
Ophthalmic Software Consulting  

R&D Expertise

• Algorithm Design for Ophthalmic Instrumentation

• Clinical Knowledge-Based Expert System Development

• Physiologic Optics

• Medical Signal and Image Processing

Software Development Expertise

• Turnkey delivery of Software Packages

•  Clinic-friendly Graphical User Interfaces

• Robust Clinical Databases

Projects Completed

08/00–Now: Full-time consultant for Advanced Medical Optics (AMO Inc., previously VISX, Inc.) Developing Wavefront Aberrometer-based Custom LASIK treatment software, used worldwide in approx 3000 LASIK centers.

10-99–07/00: Full-time consultant for Zeiss-Humphrey Systems. Developed Corneal Topography based PRK Laser treatment software.

10/97 - 09-99: Full-time consultant for Premier Laser Systems (EyeSys Vision Group), Irvine CA: Specified, designed and implemented or managed the following projects: 

•  Topography–based LASIK/PRK Ablation Planner & Simulator (in conjunction with VISX).

• Internationalization of Corneal Topographer software into German, French, Italian and Spanish.

08/92 – 09/97: Full-time consultant for EyeSys Technologies, Houston TX: Specified, designed and implemented or managed the following projects:

•   Automated RGP Contact Lens Fitting system with fluorescein simulation of Lens Fitting and database of commercial lenses. This includes automated transfer, via Internet, of patient data from clinician to lens dispenser. Product reduces patient chair time by 51%, has a 91% first-lens fit rate, and is in use worldwide.

• The Holladay Intra-Ocular Lens Consultant, comprising the expertise of three leading cataract surgeons (Drs. J Holladay, J Retzlaff, and R Hoffer). Software now in daily use by approx. 500 US & international cataract surgeons.
  

• 3-D Corneal Studio: interactive tool to allow ophthalmic surgeon to examine corneal surface shape in magnified detail.

• Surgical Planning Software series for Radial and Arcuate Keratotomy (RK & AK), comprising expertise of four leading Refractive Surgeons. Products in daily use at several hundred refractive surgery clinics.

• Designed an email application that enables clinicians to share clinical data obtained from a corneal topographer over the Internet. The application is integrated into the instrument’s software for maximum ease of use.  

09/91 - 09/92: - Full-time consultant for VisiOptics, Houston TX,: Specified, designed and assisted in the implementation of a Corneal Topography Imaging instrument, including instrument design, video image acquisition, and Contact Lens Fitting software software. VisiOptics has since been acquired by Alcon, Inc.  

12/88 - 08/91: General Partner, 4N Systems Co., Houston TX - Co-Developer of a real-time plant control system using Expert System, C++ and OOP/GUI techniques. Project involved plant simulation to provide normal and crisis management test data. 

6/84 - 11/88: Full-time consultant for Positron Corporation, Houston TX: Developed 3-D image reconstruction theory, simulation and display software for a Positron Emission Tomography scanner.  

06/88 - Now: Editorial Board Member, Addison-Wesley Publishing, Computer Science Division, and Prentice-Hall Publishing, Electrical Eng. Division.

05/82 - 09/84: Assistant Professor, Medical Imaging, dept. of Cardiology, at the University of Texas Medical School, Houston TX. Research: 3D image reconstruction from 2D cardiac images. 

9/81 - 9/84: General Partner, Software & Hardware Integration Consultants (SHIC), Houston TX. Three-member team consulting for:

•  National Aeronautics and Space Agency (NASA), Pasadena TX: Real-time Space Shuttle radio data acquisition and Fourier Analysis (9/81 - 9/82).

• University of Texas Health Science Center, dept. of Neurobiology, Houston TX: Real-time EEG data acquisition, processing and display (10/82 - 7/84).

• Woodhouse Contact Lens Co., Houston TX: Maintenance and upgrade of custom automated RGP contact lens machine tool (10/81 - 9/84).  

Academic Appointments

Adjunct Professor, Electrical and Computer Engineering dept., Rice University, Houston TX  (August 1982- June 1994).  

Courses Taught

 Medical Imaging Systems - Graduate level course at Rice University, dept. of Electrical & Computer Engineering (Spring 84), and at Texas Instruments, Dallas (Fall 86).  

Artificial Intelligence & Expert Systems: Graduate level course at Rice University, dept. of Electrical & Computer Engineering, and Texas Instruments, Houston, TX ( taught several times from Spring 86 to Spring 89 - also taught at Texas Instruments, Stafford, TX). 

Advanced Topics in Machine Intelligence: Neural Networks, Natural Language Understanding, Computational Vision - Graduate level course at Rice University, dept. of Electrical & Computer Engineering (Spring 88 and Spring 92).  

Academic Background

 Ph.D. / Biomedical Engineering, May 82, Rice University, Houston TX. Thesis topic: 3-D Simulation & Real-time Image Reconstruction for a Time-of-Flight Positron Emission Tomography (TOFPET) Scanner.  

M.S. / Biomedical Engineering, May 79, Rice University, Houston TX. Thesis topic: Microprocessor Control of an Assist System for the Profound Support of the Failing Heart.  

B.S. / Electronics Engineering, June 77, University of Essex, Colchester, Essex, England. Senior project: A Hybrid Digital/Analog Logarithmic Computer-Plotter Interface. 

Honors

University of Texas Medical School at Houston Fellowship, 1978-82.

Rice University  Graduate Studies Fellowship, 1977-78.

University of Essex Exceptional Merit Grant, 1975-77. 

Publications

1) E Philippe, JW Clark, A Lande and JR Ellis: Microprocessor Control of Intra-Aortic Balloon Pumping. Annals of Biomedical Engineering, Vol. 8, pp. 209-224, 1980.  

2) E Philippe, JW Clark, A Lande et al: Automated Microprocessor Controlled Combined Cardiac Assist in Profound Ventricular Failure. Trans Am Soc Artif Intern Organs, Vol. XXVI, 1980.  

3) JW Clark, E Philippe, R Peterson, A Lande and JR Ellis: Automatic Control of a Series-Parallel Mechanical Circulatory System in Severe Uni- or Bi-Ventricular Failure. Annals of Biomedical Engineering, Vol. 8, pp. 57-74, 1980.  

4) N Mullani, W Wong, R Hartz, E Philippe and K Yerian: Sensitivity Improvement of TOFPET by the Utilization of Inter-Slice Coincidences. IEEE Trans Nuclear Science, NS-29:479-483, 1982. 

5) E Philippe, N Mullani, R Hartz and WH Wong: Real-time Image Reconstruction for Time-of-Flight Positron Emission Tomography (TOFPET). IEEE Trans Nuclear Science, NS-29:524-528, 1982.  

6) RK Hartz, E Philippe, WH Wong, K Yerian and N Mullani: Implementation of TOFPET Real-Time Image Reconstruction.  Proc International Workshop on Time of Flight Tomography, Washington University, St. Louis, Mo. Published by the IEEE Computer Society, May 82.  

7) NA Mullani, WH Wong, RK Hartz, K Yerian, EA Philippe and KL Gould: Design of TOFPET: A High Resolution Time of Flight Positron Camera. Proc International Workshop on Time of Flight Tomography, Washington University, St. Louis, Mo. Published by the IEEE Computer Society, May 82.  

8) EA Philippe and N Mullani: Some Signal Processing Aspects of Time-of-Flight Positron Emission Tomography (TOFPET) System Implementation. IEEE Trans Nucl Sci, Vol NS-30, No 1,pp.715-719, Feb 1983. 

9) W Wong, N Mullani, E Philippe and R Hartz: Image Improvement and Design Optimization of the time-of-flight PET. J Nucl Med, 24:52, 1983.

10) N Kehtarnavaz, EA Philippe and RJP Defigureido: A Novel Surface Reconstruction and Display Method for Cardiac PET Imaging. IEEE Trans Medical Imaging, Vol MI-3, No 3, pp. 108-115, Sept 84.

Computer Languages & Operating Systems

Currently Visual C++/MFC under MS Windows XP and Vista for development, and Visual Basic for rapid GUI prototyping. Prior, have used FORTRAN under VAX/VMS, as well as LISP, Motorola 6800 and PDP-11 Assembly, and others.

Foreign Languages

French (Native Speaker), Spanish (Fluent), and Arabic (Fluent).

Professional and personal references furnished upon request.  

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